Welcome to the Ofial lab (physical-organic chemistry) at LMU München

News (@OfialLab on X)

 

Munich Postdoc Night (September 12, 2024)

Congrats to Prabaharan for being awarded for the best poster talk by the City of Munich’s Department of Labor and Economic Development!

 

Publications

Selected highlights:

• From Oxygen to Tellurium: The Impact of the Chalcogen on Nucleophilicities and Basicities of Isochalcogenourea Catalysts
  Von Sauerstoff zu Tellur: Der Einfluss des Chalkogenatoms auf die Nucleophilie und Basizität von Isochalkogenharnstoff-basierten Katalysatoren
  L. Stockhammer, K. Kasten, A. Eitzinger, L. S. Vogl, M. Piringer, D. Weinzierl, A. R. Ofial,* A. D. Smith,* M. Waser,* Angew. Chem. Int. Ed. 2025, EarlyView, e202514865.
  [download]
• Highly Nucleophilic Pyridinamide Anions in Apolar Organic Solvents due to Asymmetric Ion Pair Association
  V. Burger, M. Franta, A. R. Ofial,* R. M. Gschwind,* H. Zipse,* J. Am. Chem. Soc. 2025, 147, 5043-5050.
  [download]
• Reactivities of tertiary phosphines towards allenic, acetylenic, and vinylic Michael acceptors
  F. An, J. Brossette, H. Jangra, Y. Wei, M. Shi, H. Zipse,* A. R. Ofial,* Chem. Sci. 2024, 15, 18111-18126.
  [download]
• Pushing the Upper Limit of Nucleophilicity Scales by Mesoionic N-Heterocyclic Olefins
  A. Eitzinger, J. Reitz, P. W. Antoni, H. Mayr, A. R. Ofial,* M. M. Hansmann,* Angew. Chem. Int. Ed. 2023, 62, e202309790.
  [download]
• One-Bond-Nucleophilicity and -Electrophilicity Parameters: An Efficient Ordering System for 1,3-Dipolar Cycloadditions
  L. Li, R. J. Mayer, A. R. Ofial,* H. Mayr,* J. Am. Chem. Soc. 2023, 145, 7416-7434.
  [download]

 

Mayr's Database of Reactivity Parameters

A constantly updated collection of published reactivity parameters E, N (and s_N) for electrophiles and nucleophiles.